retinoic acid receptor beta in pathophysiology of age-related macular degeneration

نویسندگان

saeed tavakolifar

sina lasemi

sajad mohammadgholiha

zahra-soheila soheili

چکیده

no abstract.

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Retinoic Acid Receptor Beta in Pathophysiology of Age-Related Macular Degeneration.

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the genetics of age-related macular degeneration

age-related macular degeneration (amd) is the leading cause of blindness in old subjects. it is a multifactorial disease with both environmental and genetic factors playing some role in its pathogenesis. similar to many other genetic diseases, the inheritance pattern of amd does not fit into simple mendelian rules. these diseases are caused by the presence of multiple genetic factors and are ca...

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Measurement of Choroidal Neovascular Area in Age-Related Macular Degeneration using Modified Otsu’s Thresholding Method

Introduction: Age-related Macular Degeneration (AMD) is one of the most important causes of irreversible  blindness in the developed world and  prevents the affected  person from  performing simple tasks such  as  reading,  driving  and  facial  recognition.  In  the  AMD,  new  blood  vessels  grow  underneath  the  retina  in  a  process  called  choroidal  neovascularisation  (CNV).  There  ...

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Association of CFI gene polymorphism with age related macular degeneration in Northwest of Iran

Background & Aims: To investigate the association of CFI p.Gly119Arg polymorphism with Age-related macular degeneration (AMD). Materials & Methods: In this case-control study, the association of p.Gly119Arg polymorphism in CFI gene was investigated in 65 patients suffering from AMD and150 healthy age, sex and ethnicity matched unrelated people as control group. Both of the case and cont...

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بررسی اثر چندشکلی ژنتیکی xrcc7 با ریسک ابتلا به بیماریamd age-related macular degeneration))

amd بیماری تحلیل شبکیه است که عامل اصلی کوری در افراد بالای 55 سال در جهان غرب به شمار می-رود. در اثر این بیماری، لیپوپروتئین ها در شبکیه تجمع پیدا کرده و رگ زایی القاء می شود. ثابت شده است که عوامل ژنوتوکسیک محیطی مثل سیگار کشیدن، رژیم غذایی و نور در افراد پیر با زمینه ی ژنتیکی مستعد در بروز بیماری دخیل می باشند. بنابراین ما یک مطالعه ی مـورد- شاهـدی را ترتیب دادیم که شـامل 112 فرد مبتلا به am...

Association of Apolipoprotein E Alleles with Susceptibility to Age-Related Macular Degeneration in Iranian Patients

Background: We aimed here to investigate the association between alleles and genotypes of APOE and Age-related macular degeneration (AMD) development. Materials and Methods: After ophthalmological examination, 120 patients with confirmed AMD and 120 healthy controls were enrolled in the study. The polymorphic segment of APOE gene was PCR-amplified and sequenced to determine the frequency distr...

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عنوان ژورنال:
iranian journal of public health

جلد ۴۴، شماره ۱۱، صفحات ۱۵۷۰-۱۵۷۱

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